Carboplatin – Uses, Dosing, Administration, Side Effects Table of Contents1-Pharmacokinetics and Pharmacodynamics2-Cancer Types where Carboplatin is used (Indications)3-Cisplatin vs Carboplatin4-Availability and Dosing5-Why AUC is used to calculate dosing?6-Administration7-ToxicityPharmacokinetics and Pharmacodynamicscis-diammine-cyclobutanedicarboxylato-platinumt1/2 = 12 – 24 min; t1/2 = 1.3 – 1.7 hr; t1/2 = 22 – 40 hr24% Plasma Protein Binding (PPB) at 4 hours infusion90% …
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